The objective of this module is to inform policymakers and support their policymaking skills with gender-related knowledge to create an enabling environment for ICT-empowered women entrepreneurs. The module has four main sections, as well as an introduction and conclusion. The first section introduces the concepts of gender and empowerment within the context of the sustainable development goals. The second section explores the interfaces between women and information and communication technologies (ICTs), including the gender divide in the use of ICTs. The third section focuses on the processes to ensure gendersensitive policymaking, and the fourth section examines some actionable strategies to enable women’s entrepreneurship, particularly through the use of ICTs.